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Which of the following best describes the principle of informed consent as described in the belmont report? a. voluntariness, risk/benefit assessment, selection of subjects. b. comprehension, conflicts of interest, risk/benefit ratio. c. risk/benefit assessment, justification of research, comprehension. d. information, comprehension, voluntariness.

Asubject in a clinical research trial experiences a serious, unanticipated adverse drug experience. how should the investigator proceed, with respect to the irb, after the discovery of the adverse event occurrence? a. do not report the adverse drug experience to the irb since it is a common adverse experience. b. report the adverse drug experience to the irb only if there are several other occurrences. c. report the adverse drug experience as part of the continuing review report. d. report the adverse drug experience in a timely manner, in keeping with the irb's policies and procedures, using the forms or the mechanism provided by the irb.

Who is the official leader of the state?