In randomized, double-blind clinical trials of a new vaccine, rats were randomly divided into two groups. subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. after the second dose, 111 of 722 subjects in the experimental group (group 1) experienced fever as a side effect. after the second dose, 42 of 630 of the subjects in the control group (group 2) experienced fever as a side effect. does the evidence suggest that a higher proportion of subjects in group 1 experienced fever as a side effect than subjects in group 2 at the alphaequals0.01 level of significance?