A new screening test for Lyme disease is developed for use in the general population. The sensitivity and specificity of the new test are 60% and 70%, respectively. Three hundred people are screened at a clinic during the first year the new test is implemented. Assume the true prevalence of Lyme disease among clinic attendees is 10%. Calculate the following values:

The predictive value of a positive test

The predictive value of a negative test

predictive value of a positive test = 18.18%

predictive value of a negative test = 94.03%

Step-by-step explanation:

Sensitivity = 60% = 0.6

Specificity = 70% = 0.7

Let True Positive = TP

True Negative = TN

False Negative = FN

Prevalence = 10% = 0.1

Three hundred people are screened,

Total number of people having the disease,

But TP = 1.5 FN

30 = 1.5 FN + FN

30 = 2.5 FN

FN = 30/2.5

FN = 12

TP = 1.5 FN = 1.5 * 12

TP = 18

81 + TN = 270

TN = 189

To calculate the Predictive value of positive test (PPT)

To calculate the Predictive value of negative test (PNT)

the answer is b