Cushing's disease is characterized by muscular weakness due to adrenal or pituitary dysfunction. To provide effective treatment, it is important to detect childhood Cushing's disease as early as possible. Age at onset of symptoms and age at diagnosis (months) for 15 children suffering from the disease were given in the article "Treatment of Cushing's Disease in Childhood and Adolescence by Transphenoidal Microadenomectomy" (New Engl. J. of Med., 1984: 889). Here are the values of the differences between age at onset of symptoms and age at diagnosis: -24 -12 -55 -15 -30 -60 -14 -21
-48 -12 -25 -53 -61 -69 -80
Calculate a 95% confidence interval for the population mean difference, and interpret the resulting bound.