Substitution for:
x-5y=10
2x-10y=20

Since you need an isolated variable to use the substitution method, we need to re-arrange one of the equations. This will probably be easiest to do with the first one.
Add 5y to both sides of the first equation.
x=10+5y
Now, in the second equation, put in 10+5y in any spot that has an x.
2(10+5y)-10y=20
Distribute the 2 to both numbers in the parenthesis.
20+10y-10y=20
Combine like terms.
20=20
This means that the two equations are actually the same. You can see this if you multiply the whole first equation by 2
2(x-5y=10)
2x-10y=20, which is the same as the second equation. Therefore, the two equations are actually the same one.