How could the difficulty of getting to a job affect your decision to take it or not?

Because if anything is difficult, humans might try to avoid it unless it's their passion

The more difficult it is to get to a job, the less likely you are going to take it, since you want to have closer proximity to a job. It's like living somewhere in California by the coast, and getting a job in Las Vegas. No one wants that. You want a job that lets you sleep in as long as possible (if you're normal), and one that lets you get home at a decent hour. The farther away a job is, the less likely you are to take it. Unless you plan on moving to be closer. But you didn't ask about that, so take what you can get. ;) Best of luck to you.