The drag Prevnar is a vaccine meant to prevent meningitis. It is typically administered to infants between 12 and 15 months of age. Of the 710 infants,121 experienced a loss of appetite. Is there significant evidence to conclude the proportion of infants who receive Prevnar and experience of a loss of appetite is different from 0.135, the proportion of children who experience a loss of appetite with competing medications? Use α=0.01 level of significance.