Suppose a 70 kg man is exposed to 0.1 mg/m3 tetrachloroethylene in the air at his workplace. if he inhales 1 m3 /hr, 8 hours per day, 5 days per week, 50 weeks per year, for 30 years, and if tetrachoroethylene has an absorption factor of 90 percent and an inhalation potency of 2x10-3 (mg/kg/day)-1 , what would be his lifetime cancer risk? what would the risk to be a 50 kg woman similarly exposed?

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answer:

24

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the treatment of other conditions (e.g., cystic breast disease) and for other medical reasons. Mastectomy is most effective when the cancerous tumour is discovered at an early stage and the malignant cells are localized. In order to best ensure the removal of all cancerous tissue, however, a margin of tissue surrounding a tumour and, sometimes, other nearby structures are also removed. Thus, there are several types of mastectomy, the selection of procedure depending on the location and extent of the disease (determined by X ray, thermography, and other diagnostic techniques) and the nature of the cancerous cells (determined by biopsy).

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