Explain how complement generally prevents microbes from causing disease.

The complement system plays important role in body defense and provides innate and adaptive immune response to the body. The complement system is made up of many proteins found in the serum.  

The complement system performs many roles like cell lysis, clearance of immune complex and opsonization which helps in removing the foreign molecule from blood and put them in spleen and liver for lysis.

Most of the components of complement are synthesized in the liver and binds to antigen-antibody complex to form membrane attack complex(MAC) which results in cell lysis.  

Complement plays important role in phagocytosis of disease-causing microbes by phagocytic cells. By this way complement generally, prevent microbes from causing disease.

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