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Medicine, 24.04.2020 15:47 aquinomelodyr

Which process is the major reason behind this? A 54-year-old man has a squamous cell carcinoma of the right lung. Analysis of his germline DNA shows two alleles, m and n, at the microsatellite locus Z tightly linked to the p53 gene. Similar analysis of the neoplastic cells shows the presence of the m allele only. A. Germline mosaicisrnB. Loss of heterozygosityC. P53 Gene amplificationD. Pericentric inversion involving p53 and locus ZE. Point Mutation of allele n

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