How has herd immunity been altered in certain regions

The term “herd immunity” is widely used but carries a variety of meanings  Some authors use it to describe the proportion immune among individuals in a population. Others use it with reference to a particular threshold proportion of immune individuals that should lead to a decline in incidence of infection. Still others use it to refer to a pattern of immunity that should protect a population from invasion of a new infection. A common implication of the term is that the risk of infection among susceptible individuals in a population is reduced by the presence and proximity of immune individuals

Explanation:

activation of phospholipase c (plc) indirectly increases intracellular ions through inositol triphosphate (ip3).