an oncologist ordered 5FU 12 mg/kg IV qd x 4 d for a 180 # man. 5FU is available in 10 mL vials with a concentration of 50 mg/mL. How many mL will the patient need per dose

The answer to the question is

19.6 ml

Explanation:

Patient of weight = 180 pounds

converting to Kg;

= 180/2.2= 81.81 kg approximately

The ordered dose= 12 mg /kg

In mg, it will be;

= 12mg× 81.81 kg= 981.72mg

The available dose= 50mg

and

The available volume= 1 ml

The required dose = ( the ordered dose/ the available dose) × the available volume

Imputing the values given,we have;

=( 981.72mg/50mg)× 1ml

which is;

= 19.63 ml

and that is approximately 19.6ml to be administered.