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Medicine, 22.09.2021 14:00 glogaming16

Name three anatomical/physiological or biochemical reasons why the liver is a frequent target organ of many chemical-induced toxicities. Explain how the selective induction of either Phase I (oxidative enzymes - e. g., cytochrome P-450) or Phase II (conjugative enzymes - e. g., glutathione transferase) enzymes can increase the toxicity of some chemicals while decreasing the toxicities of others.

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