If you transfer a liter of oxygen into a 2 liter container and the gas expands to fill the entire container. does the density of the oxygen change?

Yes, the density of the oxygen change because it is a gas and the volume would depend on the size of the container. Density is mass per volume of a substance. So, as the volume changes a corresponding change in the density would be observed.

Multiply the 3 dimensions, assuming it is a rectangular cuboid, to get the volume in cm³ divide mass by volume to get density in g/cm³

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