If you take aspirin while you are drinking alcohol you may feel

Gastrointestinal problems and heartburn.

Explanation:

Gastrointestinal problems can be a result of mixing aspirin and alcohol. Some examples of this can be nausea and vomiting. The combination of aspirin and alcohol can also produce worsen ulcers, heartburn, or stomach upset. Even though these effects are not extremely dangerous, people should avoid them.

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