Isabel was born in a poor family. she had to face many adversities in life, but she never let any loss or setback affect her performance at school or at work. she always showed great courage in dealing with difficulties in her life, and she has now grown to become a very capable and responsible person. this shows her:

Awaiver of the requirement for documentation of informed consent may be granted when: the investigator has no convenient place to store signed consent forms separate from the research datathe only record linking the subject and the research is the consent document and the principal risk is a breach of confidentiality.potential subjects might find some of the research questions embarrassing, personal, or intrusivethe subjects are literate in their own language; however, they do not read, write, or speak english

“dear sir: it is with great reluctance, i trouble you on a subject, which does not fall within your province; but it is a subject that occasions me more distress, than i have felt, since the commencement of the war; and which loudly demands the most zealous exertions of every person of weight and authority, who is interested in the success of our affairs. i mean the present dreadful situation of the army for want of provisions, and the miserable prospects before us, with respect to futurity. it is more alarming than you will probably conceive, for, to form a just idea, it were necessary to be on the spot. for some days past, there has been little less, than a famine in camp. a part of the army has been a week, without any kind of flesh, and the rest for three or four days. naked and starving as they are, we cannot enough admire the incomparable patience and fidelity of the soldiery, that they have not been ere this excited by their sufferings, to a general mutiny or dispersion. strong symptoms, however, discontent have appeared in particular instances; and nothing but the most acitive efforts every where can long avert so shocking a catastrophe.” what’s the central idea?

  following the agreement that was reached in the treaty of indian springs in 1825, chief william mcintosh lost his life. why did this happen