Investigator a conducts research on emphysema using biospecimens from human subjects. the consent form indicates that the research will focus exclusively on emphysema. investigator b wishes to use the biospecimens for research on lung cancer. can investigator b use the specimens for cancer research without re-consent if the specimens are de-identified? - no, the original research subjects must be re-consented for the cancer research. - yes, because research with biospecimens is minimal risk. - yes, if the biospecimens are de-identified then the research is no longer considered human subjects research. - no, because it would be unethical to conduct research that is not consistent with the consent form the subjects originally signed.