The hands-off era is said to have ended in 1970 when a federal district court declared in the case the entire Arkansas prison system "so inhumane as to be a violation of the Eighth Amendment bar on cruel and unusual punishment."

Holt vs. Sarver

Explanation:

Based on the information provided within the question it can be said that the court case that is being pointed to in this scenario is the Holt vs. Sarver case. This was a court decision which would ultimately become the first of many cases where the court would find the entire state prison systems in violation of prisoners' constitutional rights with them being accused of  inflicting cruel and unusual punishment to the prisoners.

answer; chemical substances that affect our psychological state;