The main difference between the animation used in The Nightmare Before Christmas and Spirited Away is that The Nightmare Before Christmas was made using .

Puppets and stop-motion  

Explanation:

The puppet animation is a very famous and common technique that is used to stop motion. The model is manipulated. The model imitates by the incremental adjustment of the limbs and the expression of each frame. This is a multidisciplinary and very unique and creative art that is made by this puppet technique.

If it is done professionally then it includes sewing, sculpturing, drawing, building, molding. The modern industry focus on the stander ed puppet and the studios worldwide. Thus there is a difference between the animation used in the nightmare before Christmas and spirited away. away is that the nightmare before Christmas was made by using the puppet and stop motion.

im not sure sorry sorry