Most drugs of abuse flood the circuits of the reward center in the brain with ; some drugs also reduce the level of after long term use and causes .

feeling of pleasure, dopamine, tolerance

Explanation:

Drugs of abuse causes the brain to produce neurotransmitters called dopamine, this neurotransmitter produces a sense of pleasure. The constant intake of drugs increases the tolerance of drug and the body requires more dose so as to experience the desired effect. Drug abuser may need more amount of drug than before to experience the same level of dopamine to get high.

the best and most correct answer among the choices provided by the question is the second choice "less supportive to the war of 1812"

the war of 1812 was a military conflict that lasted from june 1812 to february 1815, fought between the united states of america and the united kingdom, its north american colonies, and its native american allies.

i hope my answer has come to your . god bless and have a nice day ahead!

answer; (false);