Two ways in which some cultural views that exist may affect a relationship negatively ​

1. In some religions men are seen as the superior to women and control them. (Women are seen as weak minded and fragile)

2. Religion is a big one. A lot of cultures won’t allow you to marry someone from a different religion and some people don’t want to marry a person who doesn’t have the same religion.

3. Cultural view brings about racial differences which deteriorate the relationship between diverse races

You can choose whichever two you prefer. :)