Suppose you have binding of a certain Kd. If you wanted to change the molecule so it bound more tightly you might have an effect either on the "on rate constant " or the "off rate constant" or both. To increase affinity how these rate constants need to change? Drugs normally act by binding to some receptor or enzyme. Suppose a drug is given so that its concentration in cells is around the Kd for the ligand that it binds to. How much more effect could you expect if you gave 10X as much drug. What else might you expect to happen

50% because no one is smart enough to relize that money makes the world go round and 99% of the earth hates donald trump the other 1% is the republicans go figure right

the answer would be in this answer. someone already asked the question.  

answer; self-efficacy;

answer: ‘no one should be discriminated against because he or she is not from a minority group’

because—> affirmative action means ‘a policy or program that provides opportunities for traditionally disadvantaged groups to them overcome the effects of discrimination’