Help on these questions please?

In the us, who’s pays income taxes? how are payroll taxes part of the income tax that workers pay to the federal government?

Aresearcher proposes to conduct a study at a foreign site. the research has been determined to be exempt from the federal regulations by institutional policy. according to federal regulations, is review required at the foreign site? if a proposed study qualifies for exemption, federal regulations do not require review at the foreign site where it will be conducted but still require review at the u.s. site by the institution’s irb. if a proposed study qualifies for exemption, federal regulations do not require review at the foreign site where it will be conducted. if a proposed study qualifies for exemption, federal regulations do require review at the foreign site where it will be conducted. if a proposed study qualifies for exemption, federal regulations do not require review at the foreign site where it will be conducted, but still require review by the institutional official at the local site.

Why is james madison significant in regards to the bill of rights?