After charles darwin began suffering panic disorder, he lived in relative seclusion and traveled only in his wife's company. his panic disorder was apparently accompanied by

His panic disorder was apparently accompanied by "agoraphobia".

Agoraphobia refers to a kind of nervousness issue in which you fear and keep away from spots or circumstances that may make you frenzy and influence you to feel caught, powerless or humiliated. Individuals with agoraphobia frequently have indications of a fit of anxiety, for example, a quick pulse and queasiness, when they end up in an upsetting circumstance.

The answer for this question is c

An informal structure in a bureaucracy would be something like so-called "office politics". where there's a formal structure set up for the organization, but then an informal subculture as well that has a way of organizing the bureaucracy further. this can be positive because it sets up an added degree of organization, albeit informal, within the bureaucracy.