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Biology, 18.03.2020 18:31 suxy16

G protein‑coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) are two basic receptor types by which cells transduce signals. Classify each statement as describing GPCRs, RTKs, both types of receptors, or neither.

1) phosphorylation of receptor can terminate signal or desensitize receptor
2) autophosphorylation of receptor can initiate signal
3) structure contains seven transmembrane helices
4) ligand binding induces conformational change in receptor
5) receptor activation causes phosphorylation of its cytosolic subunits
6) an example is the insulin receptor
7) transports some ligands through the membrane
8) an example is the epinephrine receptor
9) activate heterotrimeric G proteins directly

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