Construct a hypothesis to explain the differences you might observe when comparing the karyotypes of normal human cells versus cancerous cells

The karyotype of cancerous cells is abnormal due to the mutations in the DNA. The cell division that occurs in the cancerous cells is similar to the normal cell division. The only difference lies in the check points. The cancerous cells skip the checkpoints where the errors are checked.

Further Explanation:

A hypothesis is the primary explanation that is formed on the basis of limited evidences that support the investigation.

The picture of a person’s chromosome is known as karyotype. The karyotype of a person can be determined by isolation of chromosomes followed by staining and examination of the chromosomes under microscope. The WBC chromosomes are usually isolated, stained and examined. The examined picture under a microscope is taken and the chromosomes are then arranged in the decreasing order of chromosome size. In a normal cell, the mitosis cell division also known as equational cell division is responsible for the increase in the number of cells. The number of chromosomes after the mitotic cell division remains equal to the initial number of chromosomes. Thus, known as equational cell division. In cancerous cells, the abnormal mitosis cell division occurs in which the cell skips the checkpoints which causes abnormal number of mitotic divisions.

Thus, the karyotype of cancerous cells is abnormal due to the mutations in the DNA. The cell division that occurs in the cancerous cells is similar to the normal cell division. The only difference lies in the check points. The cancerous cells skip the checkpoints where the errors are checked.

Learn more:

    •    Learn more about meiosis link

    •    Learn more about scientific theory

         link

    •    Learn more about mitosis and binary fission

         link

Answer Details:

Grade: High School

Subject: Biology

Chapter: Cell Division

Keywords:

Hypothesis, evidences, investigation, cancerous cells, mitosis, equational cell division, chromosomes, check points, microscope, mutations, isolation, staining.

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