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Biology, 04.11.2020 18:30 postorivofarms

Activation of the GTPase Cdc42 leads to a different set of actin rearrangements from those brought about by activation of the GTPase Rho. It is known that Arp2/3 proteins are targets of Cdc42, whereas Formins are targets of Rho1. Both Arp2/3 and Formins promote actin polymerization. Explain why the activation of these two GTPases could lead to differences in the actin cytoskeleton.

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