How does an error in meiosis result to cri-du-chat.

Meiotic errors are alterations of a cell's chromosome number or structure. Chromosomal alterations happen in both mitosis and meiosis. But in some ways meiosis provides more opportunities for errors. This is because the three sources of genetic variation in meiosis can also be opportunities for errors. Crossing over in prophase I and independent assortment in anaphase I and anaphase II are major sources of genetic variation among sexually reproducing organisms. Each sexually reproduced organism is genetically unique, unlike the genetically identical offspring in mitosis. The benefits of having multiple sources of genetic variation are diversity and enhanced adaptability to changing environments. But crossing over and independent assortment can also provide opportunities for errors, resulting in gametes with altered structures or numbers of chromosomes. The consequences of meiotic errors can be mild or fatal; they will be discussed in the last section.

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