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The instructions on the tpa vials read to reconstitute with 50 ml of sterile water to make a total of 50 mg/50 ml (1 mg/ml). the hospital protocol is to infuse 0.9 mg/kg over 60 minutes with 10% of the dose given as a bolus over 1 minute. n. t. weighs 143 pounds. what is the amount of the bolus dose, in both milligrams and milliliters, that you will administer in the first minute? what is the amount of the remaining dose that you will need to administer?
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