As a technician in a large pharmaceutical research firm, you need to produce 250. ml of a potassium dihydrogen phosphate buffer solution of ph = 7.05. the pka of h2po4− is 7.21. you have the following supplies: 2.00 l of 1.00 m kh2po4 stock solution, 1.50 l of 1.00 m k2hpo4 stock solution, and a carboy of pure distilled h2o. how much 1.00 m kh2po4 will you need to make this solution? (assume additive volumes.)

We will need 147.772 mL of KH2PO4 to make this solution

Explanation:

For this case we can give the following equation:

H2PO4 - ⇄ H+ + HPO42-

With following pH- equation:

pH = pKa + log [HPO42-]/[H2PO4-]

7.05 = 7.21 + log [HPO42-]/[H2PO4-]

-0.16 =  log [HPO42-]/[H2PO4-]

10^-0.16 = [HPO42-]/[H2PO4-]

0.6918 = [HPO42-]/[H2PO4-]

Let's say the volume of HPO42-= x  then the volume of H2PO4- will be 250 mL - x

Since both have a concentration of 1M = 1 mol /L

If we plug this in the equation 0.6918 = [HPO42-]/[H2PO4-]

0.6918 = x / (250 - x)

0.6918*250 - 0.6918x = x

172.95 = 1.6918x

x = 102.228 mL

The volume of HPO42- = 102.228 mL

Then the volume of H2PO4- = 250 - 102.228 = 147.772 mL

To control this we can plug this in the pH equation

7.05 = 7.21 + log [HPO42-]/[H2PO4-]

7.05= 7.21 + log (102.228 / 147.772) = 7.05

We will need 147.772 mL of KH2PO4 to make this solution

when 25.0 ml of 0.700 mol/l naoh was mixed in a calorimeter with 25.0 ml of 0.700 mol/l hcl, both initially at 20.0 °c, the temperature increased to 22.1 °c. the heat capacity of the calorimeter is 279 j/°c.

the equation for the reaction is:

naoh + hcl → nacl + h₂o

moles of hcl = 0.0250 l hcl ×

0.700

mol hcl

1 l hcl = 0.0175 mol hcl

volume of solution = (25.0 + 25.0) ml = 50.0 ml

mass of solution = 50.0 ml soln ×

1.00

ml soln

= 50.0 g soln

δt=t2-t1

= (22.1 – 20.0) °c = 2.1 °c

the heats involved are

heat from neutralization + heat to warm solution + heat to warm calorimeter = 0

q1+q2+q3=0

nδh+mcδt+cδt=0

0.0175 mol ×

δh

+ 50.0 g × 4.184 j·g⁻¹°c⁻¹ × 2.1 °c + 279 j°c⁻¹ × 2.1 °c = 0

0.0175 mol ×

δh

+ 439.32 j + 585.9 j = 0

0.0175 mol ×

δh

= -1025.22 j

δh=1025.22j0.0175 mol= -58 600 j/mol = -58.6 kj/mol

i think its 5049.

i hope this !