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Worth 20 points

Consider the reaction 2x2y2+z2⇌2x2y2z which has a rate law of rate= k[x2y2][z2] select a possible mechanism for the reaction.

Researchers were interested in whether relaxation training decreases the number of headaches a person experiences. they randomly assigned 20 participants to a control group or a relaxation training group and noted the change in number of headaches each group reported from the week before training to the week after training. which statistical analysis should be performed to answer the researchers' question?

[10 points, algebra 2-simplifying complex fractions]according to my answer key the restrictions are -1 and 4. but why not positive 1?