Scientific knowledge is generally considered to have a positive effect on society. in which situation would scientific knowledge most likely have a negative effect on society?

Scientific knowledge itself cannot have a positive or negative impact on society per se. What can have a negative or positive impact is how this knowledge is being used. 

While we all enjoy a beter life due to advancements in medicine and technology for example, this was because people decided they would put certain scientific discoveries into practice and spread them among the people.

The same thing can also be said for negative scientific discoveries. While energy produced in atomic power plants per se isn't harmful, when making an atomic bomb out of it, it can be disastrous. It was the intention of doing something evil with it that might have had a negative impact on society, not the knowledge itself. 

Edit the post so i can see the letters for each answer, and increase the points required so i'd be able to answer it.

This did i unseated, sorry