What results would you expect if such inside-out vesicles were subjected to the lp/125i procedure? what results would you expect if such inside-out vesicles were subjected to the procedure? you would expect to see labeling of all the proteins, because almost all membrane proteins are accessible from one side of the membrane or the other. you would expect only oxidation of lactose groups with lp, because 125i is too polar and wouldn't be able to penetrate through hydrophobic membrane. you would expect no labeling, because all membrane proteins are associated with the outer layer and would therefore be on the interior of an inside-out vesicle.